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Immunotherapy

New CAR T Strategy Targets Tumor Macrophages, Triggers Antitumor Immunity in Mice

Researchers report durable tumor regressions in multiple mouse models using an antigen‑independent, macrophage‑targeted approach.

Study Identifies TSP‑1–CD47 Signal That Drives T‑Cell Exhaustion in Cancer

mRNA COVID Vaccines Tied to Longer Survival With Checkpoint Immunotherapy, Nature Study Reports

mRNA COVID Vaccines Linked to Longer Survival With Checkpoint Immunotherapy, Peer‑Reviewed Study Finds

mRNA COVID Vaccination Linked to Longer Survival With Cancer Immunotherapy, Data Presented at ESMO

Nanoparticle 'Super Adjuvant' Vaccine Blocks Multiple Cancers in Mice

UMass Amherst Dual-Adjuvant Nanoparticle Vaccine Blocks Tumors and Metastasis in Mice

Dual-Adjuvant Nanoparticle Vaccine Prevents Multiple Cancers in Mice, Blocks Metastasis

Engineered CAR-T Cells Target PD-L1 to Deliver IL-12 at Tumors, Showing Solid-Tumor Gains in Mice

Glycan-Targeting ‘GlyTR’ Therapy Kills Diverse Cancers in Preclinical Tests

Tumor-Induced Nerve Injury Identified as Driver of Anti–PD-1 Resistance

KRAS-Targeted Vaccine Shows Robust Immune Response, Longer-Than-Expected Survival in Pancreatic and Colorectal Cancer Trial

AI-Informed Pipeline Accelerates Bi-Specific CAR-T Design and Clears Tumors in Mice

mRNA Neoantigen Vaccine Amplifies Anti-PD-1 Immunity and Suppresses Gastric Cancer Spread in Mice

Off-The-Shelf KRAS Vaccine Yields Robust T-Cell Responses and Survival Benefit

CDK12/13 Degraders Activate STING-Mediated Immunity and Enhance Checkpoint Therapy

Researchers Plan Trials to Counteract Sucralose’s Impairment of Cancer Immunotherapy

UF Researchers Develop Universal mRNA Vaccine That Primes Immune System Against Tumors

Exercise-Induced Formate from Gut Microbes Enhances Cancer Immunotherapy

moPepGen Graph Algorithm Quadruples Protein Variant Detection in Tumor Samples