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Colorectal Cancer

DR5–Lig3 Feedback Loop Explains Why MSI Colorectal Tumors Respond to Immunotherapy

Tumor cell death releases circular DNA that boosts immune sensing, pointing to drug and biomarker strategies for testing.

Tumor Inflammation Drives Early Resistance to KRAS Drugs, Study Shows

Mayo-Led Study Links PNPLA3 Variant to Chemotherapy-Related Liver Injury in Colorectal Liver Metastases

Atezolizumab-Enhanced Chemotherapy Halves Recurrence in Stage III dMMR Colon Cancer

Triplet Therapy Doubles Survival in BRAF V600E Metastatic Colorectal Cancer