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WHO-Backed Analysis Finds 38% of 2022 Cancer Cases Attributable to Modifiable Risks

The findings highlight concrete levers for prevention, with tobacco control, vaccination and cleaner environments expected to cut future cases.

Overview

  • In the Nature Medicine study using GLOBOCAN 2022 data, 7.1 million of 18.7 million cancer diagnoses were linked to 30 changeable factors, including nine infections.
  • Smoking was the largest contributor at about 15% of new cases worldwide, followed by infections at roughly 10% and alcohol at about 3%.
  • Preventable fractions differed by sex, accounting for an estimated 45.4% of cancers in men and 29.7% in women, or 4.3 million and 2.7 million cases respectively.
  • Lung, stomach and cervical cancers together made up nearly half of the cases tied to these modifiable risks.
  • Contributions varied by region, with infections leading in 141 countries, tobacco’s impact highest in Northern Europe and North America, and high BMI accounting for a larger share in North America than globally.