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University of Toronto Engineers Develop PDMS 'Bristle' Coating That Repels Proteins

Researchers say the biocompatible design could cut reliance on PFAS coatings once validated.

Overview

  • Lab tests using bovine serum albumin showed the surface stopped protein buildup, with results published in the Chemical Engineering Journal.
  • Long, flexible PDMS chains stand like soft bristles and create a “liquidlike” interface that keeps sticky proteins from gripping.
  • As protein-laden droplets dried on the coated glass, residues shrank and then flaked off with a light puff of air or a water rinse.
  • In head-to-head trials, the coating outperformed PFAS-based non-stick treatments, signaling a potential safer option than chemistries linked to health risks.
  • The team is pursuing pathogen testing and manufacturing partners to scale production, and it disclosed partial funding from Meltech Innovation Canada Inc., part of the Medicom Group.