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UK Regulator Caps Use of Nasal Decongestant Sprays at Five Days

Regulators cite harms from overuse, including rebound congestion that worsens blockage.

Overview

  • The MHRA, which announced the change Thursday, will add a five-day limit to new packs and leaflets over the coming months while existing stock may still show seven days.
  • The decision follows advice to the Commission on Human Medicines after evidence that longer use can cause rebound congestion, where swollen nasal tissues get worse with continued spraying.
  • The rule covers over-the-counter sprays and drops with xylometazoline or oxymetazoline, which are sold for short-term relief of colds, allergies and sinusitis.
  • People are urged to follow the five-day limit now, speak to a pharmacist or GP if a blocked nose lasts, and report side effects to the MHRA Yellow Card scheme.
  • Research by Ipsos and ITV News found over a fifth of users exceeded a week of use, putting an estimated 5.5 million people in the UK at risk of dependence.