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Twist Bioscience Lifts 2026 Outlook After Q2 Beat, Reaffirms Q4 EBITDA Breakeven

AI-led drug discovery is fueling faster uptake of Twist’s lab tools.

Overview

  • Twist Bioscience, which reported second‑quarter results Monday, posted revenue of $110.7 million, up 19% year over year and its 13th straight quarter of sequential growth.
  • The company raised full‑year sales guidance to $442 million–$447 million and kept its goal of adjusted EBITDA breakeven in fiscal Q4 2026, with third‑quarter sales projected at $114 million–$115 million.
  • DNA Synthesis and Protein Solutions grew 28% to $53.3 million and next‑generation sequencing rose 12% to $57.4 million, helped by AI projects and oncology tests that track minimal residual disease after treatment.
  • Profitability pressures persisted as the adjusted loss came in at $0.59 per share and the company booked $7.2 million toward a $17.1 million securities class‑action settlement that it expects insurers to cover beyond the amount recorded.
  • New demand signals included an AWS partnership that names Twist the wet‑lab partner for Amazon BioDiscovery, a role that could steer more AI drug discovery work to its synthesis and protein platforms.