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Tohoku University Team to Launch Investigator-Led Trial of New Mitochondrial Disease Drug in December

The small multi-site study will enroll 15 patients with hearing loss at four Japanese hospitals.

Overview

  • The trial will assess safety and whether the investigational therapy can slow disease progression and improve hearing.
  • Sites include Jichi Medical University Hospital in Tochigi Prefecture as part of a four-facility network.
  • Researchers described mitochondrial disease as a rapidly progressive, severe rare condition with significant unmet need.
  • Professor Takaaki Abe said successful drug development could offer hope to patients and families.
  • The team noted mitochondrial dysfunction also features in age-related and noise-induced hearing loss, suggesting potential wider relevance if benefits are observed.