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Teen Cannabis Use Tied to Slower Cognitive Growth in Largest U.S. Youth Brain Study

A large U.S. youth brain study using combined self-report plus toxicology points to THC exposure as the likely driver of teen memory declines.

Overview

  • Published Monday in Neuropsychopharmacology, the peer‑reviewed analysis followed more than 11,000 ABCD participants from ages 9–10 to 16–17 and will continue into young adulthood.
  • Teens who began using cannabis showed smaller gains over time in memory, attention, language, and processing speed compared with peers who did not use.
  • In many cases early scores were similar, but progress flattened after cannabis use started while classmates kept improving.
  • Biological tests alongside surveys detected exposure, and THC evidence tracked with worsening memory over time, while CBD did not show that pattern.
  • The authors controlled for prior cognition, family background, mental health, and other substance use, and they cautioned the results do not prove direct causation.