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Study Finds Wine Linked to Lower Risk at Modest Intake, Unlike Beer or Spirits

Researchers analyzing 340,924 UK Biobank participants over more than 13 years caution that the findings are observational, recommending randomized trials before any change in guidance.

Overview

  • High alcohol consumption was associated with a 24% higher risk of death from any cause, a 36% higher risk of cancer death, and a 14% higher risk of cardiovascular death compared with never or occasional drinkers.
  • At low to moderate intake, beverage type differed: wine was linked to lower mortality while similar amounts of beer, cider, or spirits were linked to higher mortality.
  • For cardiovascular outcomes, moderate wine drinkers had a 21% lower risk of dying from heart disease versus never or occasional drinkers, whereas even low intake of beer, cider, or spirits was tied to a 9% higher risk.
  • Analyses adjusted for demographics, socioeconomic status, lifestyle, cardiometabolic factors and family history, though alcohol use was self-reported at baseline and the UK Biobank cohort is healthier than the general population.
  • Authors noted possible explanations such as red-wine polyphenols and drinking with meals, and the study will be presented at ACC.26 on March 28 in New Orleans.