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Study Finds ‘Metabolically Healthy’ Childhood Obesity Still Carries High Long-Term Disease Risk

The results point to offering treatment to all children with obesity to cut later disease risk.

Overview

  • The JAMA Pediatrics cohort study, published Monday, followed more than 7,200 Swedish children who began obesity treatment at ages 7–17 through age 30.
  • Children labeled metabolically healthy at treatment start still showed higher rates by age 30 of type 2 diabetes (9%), hypertension (11%), and abnormal blood lipids (5%) than general-population peers (0.5%, 4%, 1%).
  • Risk fell when a child’s BMI z-score dropped during treatment, and the size of that benefit was the same for metabolically healthy and unhealthy groups.
  • All participants received lifestyle support, and the authors recommend offering treatment to every child with obesity even when blood tests and blood pressure look normal.
  • The analysis drew on Sweden’s BORIS pediatric obesity registry linked to national health records, providing long-term outcome data that can inform clinical guidelines and public health policy.