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South Carolina Ends Measles Outbreak After 997 Cases

The declaration underscores how gaps in vaccination allow large outbreaks despite measles previously being eliminated in the United States.

Overview

  • State health officials, who declared the outbreak over Monday, did so after 42 days passed with no new cases since the last infection on March 15.
  • The six-month outbreak reached 997 cases, including 932 people who had never been vaccinated, with more than 90% of infections in Spartanburg County.
  • Children aged 5 to 17 made up the largest share of patients, with 639 infections concentrated in schools and youth activities.
  • The response led to quarantines of 874 students across 33 schools and an estimated $2.1 million in state costs.
  • Vaccination rose sharply during the response with more than 81,000 measles doses given statewide, a 31% increase from 2025, as the CDC assisted the state and regional officials review the U.S. elimination status with a decision expected in November after national cases totaled 2,288 in 2025 and 1,792 so far this year.