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Sleep Loss Tied to Small Weight Gain and More Sitting in Adults at Cardiometabolic Risk

The pooled clinical analysis suggests sleep duration is a modifiable factor that should be considered in efforts to prevent weight gain and heart and metabolic disease.

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Una mujer durmiendo, en una imagen de archivo.
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La relación un sueño suficiente y el control de nuestro peso es todavía estudiada.

Overview

  • A pooled analysis published in early July 2026 combined two randomized, within-subject trials that asked 95 adults with cardiometabolic risk to sleep normally for six weeks and then reduce sleep by about 1.5 hours per night for six weeks.
  • Compared with their usual sleep, participants gained about 0.5 kg on average and showed a small rise in waist circumference after six weeks of modest sleep restriction.
  • Objective wrist monitoring showed daily sedentary time rose by roughly 17 minutes overall and by nearly 30 minutes in men and postmenopausal women, pointing to less spontaneous activity as a behavioral pathway.
  • Secondary analyses found signals of increased insulin resistance and markers of cardiac inflammation in some subgroups, with stronger effects reported in postmenopausal women.
  • Researchers note the trial’s strengths—randomized within-person design and objective activity measures—but warn the small sample (N=95) and the high-risk participant group limit generalizability and call for larger, longer studies to test long-term health effects and mechanisms.