Singapore’s PRECISE‑SG100K Enlists Seer and Thermo Fisher for Population‑Scale Proteomics

Overview

• PRECISE‑SG100K, which detailed the proteomics build‑out Thursday, will use Seer’s Proteograph to deeply profile plasma from 10,000 participants.
• Thermo Fisher will apply Olink Proximity Extension Assay protein panels and its Orbitrap Astral mass spectrometers on the same samples to pair targeted tests with deep discovery.
• The project will merge data from the affinity panels and the mass spectrometry runs to cross‑validate signals and raise confidence in biomarker findings.
• The Singapore cohort has completed recruitment of more than 100,000 multi‑ethnic residents with baseline samples and data for long‑term health tracking.
• Novogene will provide laboratory services for sample processing, and Thermo Fisher brings large‑biobank experience from efforts such as UK Biobank and FinnGen to help scale the work.