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Singapore Confirms First Local Mpox Cases of Clade 1b

Officials plan contact tracing with post-exposure vaccination for high-risk contacts.

Overview

  • The Communicable Diseases Agency, which announced the infections Thursday, said the risk to the general public is low because mpox spreads through intimate or prolonged contact.
  • Two men aged 30 and 34 developed symptoms on Mar 25 and 26 after prolonged physical contact, with one having recently traveled, and both are isolating at home until Apr 20 and 21.
  • Investigations and contact tracing are under way, close contacts were told to monitor their health, and high-risk contacts will be offered vaccination after exposure.
  • Clade 1b is considered more severe than clade 2 and was first identified in September 2023 during surges in parts of Africa, and Singapore recorded 23 cases in 2025 and seven by Mar 21, 2026.
  • Vaccines are available to higher-risk groups at four named clinics now, with access at the National Centre for Infectious Diseases starting in May, and officials advise avoiding high-risk sexual activity and taking travel precautions.