Overview
- Duke, Arizona, Michigan and Florida received the four No. 1 seeds following the 68‑team bracket reveal.
- The First Four is scheduled for March 17–18 in Dayton, with first and second rounds in Buffalo, Greenville, Oklahoma City, Portland, Tampa, Philadelphia, San Diego and St. Louis, and the Final Four set for April 4–6 in Indianapolis.
- Opening odds posted Sunday night listed Duke as a frontrunner at +330 on DraftKings, with Michigan, Arizona and Florida close behind, while BetMGM pricing showed Michigan narrowly shorter than Duke.
- Notable first‑round pairings include No. 1 Duke vs. No. 16 Siena, No. 1 Arizona vs. No. 16 LIU, and No. 1 Michigan awaiting the UMBC/Howard winner from the First Four.
- The Selection Committee awarded automatic bids to conference champions such as Gonzaga, Arkansas, VCU, Purdue, Duke, Arizona, South Florida, High Point and Siena.