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Scientists Partner to Test Gene Editing and Vaccine to Protect Tasmanian Devils

A University of Tasmania–Colossal collaboration will investigate whether editing a devil-specific mutated gene can reduce susceptibility to the transmissible facial tumour.

Overview

  • The new partnership will combine genetic research, vaccine development, and captive trials to tackle devil facial tumour disease, a contagious cancer that has cut wild populations by about 80 percent.
  • Researchers plan to study a mutated devil gene linked to cancer susceptibility and may test editing or replacing that gene with one from the fat-tailed dunnart if laboratory results support the approach.
  • Colossal is funding a dedicated fat-tailed dunnart colony in Hobart to serve as a safer test species for gene and vaccine work before any experiments on endangered devils.
  • An oral vaccine program is progressing in parallel with genetic work and captive vaccine trials are slated to begin by the end of 2026, according to project leads.
  • Scientists and partners stress multi-year, tightly controlled captive testing and stepwise monitoring before any release of genetically altered devils, with wild release not expected for many years to avoid unintended consequences.