Overview
- O'Donnell confirmed in a People interview published Tuesday that she began using the GLP-1 drug Mounjaro in 2023 after a Type 2 diabetes diagnosis and lost nearly 60 pounds over roughly three years.
- She told the magazine that Mounjaro "quieted the food noise" and that the treatment changed how she eats and feels about her body.
- O'Donnell quietly had a deep plane lower facelift to remove excess skin from the weight loss and disclosed a reported cost of $90,000 while saying she worried about the expense.
- She first acknowledged the surgery in a May Substack post where she described guilt and shame, and she says she "wrestled" with the choice because of feminist concerns and her child's reaction before deciding it was her decision.
- Mounjaro is a once-weekly injectable used to treat Type 2 diabetes that reduces appetite by increasing fullness, and O'Donnell's public details feed into ongoing debates about celebrity use, access to GLP-1 drugs, and the common medical need for cosmetic surgery after large weight loss.