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Regeneron and Telix Form 50/50 Partnership to Develop Targeted Radiopharmaceuticals

The tie-up points to growing big‑biotech interest in cancer drugs that deliver radiation directly to tumors and demand specialized manufacturing.

Overview

  • The companies announced a co-development deal with a 50/50 split of costs and profits that includes a $40 million upfront payment from Regeneron for four initial therapy programs.
  • Regeneron holds an option to add four more programs beyond the initial slate, which would trigger additional upfront payments.
  • Telix can opt out of co-funding any program in exchange for up to $535 million in development and commercial milestones per program plus low double-digit royalties, with aggregate milestones across the deal reaching up to $2.1 billion.
  • The collaboration pairs Regeneron’s antibody platforms, including VelocImmune and bispecifics, with Telix’s radiopharma manufacturing network to create drugs that carry a radioactive payload to cancer cells while sparing more healthy tissue.
  • The partners will also build imaging tools to select patients and track response, with Telix leading commercialization and Regeneron receiving a share of profits, and they did not announce trial start dates or regulatory filings.