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Prue Leith Ends Mounjaro Trial After No Weight Loss in a Month

She blames ignoring calorie guidance for the failure, describing profound appetite suppression that left her lethargic.

Overview

  • The 86-year-old tried the prescription weekly injection for a month and then stopped, calling it expensive and not a fit for her life.
  • She says she ate roughly 200 calories a day instead of the advised intake, which she believes put her into 'starvation mode' with no pounds lost.
  • Leith reported severe appetite loss and fatigue, saying she sometimes did not want to get up while on holiday.
  • Her husband, John Playfair, has lost about three stone using Mounjaro, which motivated her to try the drug despite her different outcome.
  • She still considers medically supervised weight-loss jabs 'worth a go' for others, as she departs The Great British Bake Off with Nigella Lawson confirmed as her replacement.