Overview
- Researchers tracked more than 500,000 adults for about 14 years, during which 675 people developed ALS.
- Morning chronotype was associated with a 20% lower risk of ALS compared with evening chronotype after statistical adjustments.
- Achieving at least 600 MET‑minutes of physical activity per week was linked to a 26% lower risk, based on standardized MET scoring.
- Sleeping six to eight hours per night was associated with lower ALS risk than shorter or longer sleep durations.
- The findings show associations rather than causation, the cohort was 95% white, and the results are slated for presentation at AAN’s April meeting.