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Okava Launches First GLP-1 Implant Trial for Overweight Cats

The FDA-monitored MEOW-1 study plans about 50 enrollees over three months, with initial results expected next summer.

Overview

  • Okava says the first cat has received OKV-119, a tiny subcutaneous implant designed to release a GLP-1 drug for up to six months.
  • The pilot intends to enroll roughly 50 overweight or obese cats for a three-month observation period with an optional three-month extension.
  • The study is conducted under the FDA’s Investigational New Animal Drug oversight to evaluate safety, tolerability, and weight-loss efficacy, led by Dr. Chen Gilor at the University of Florida.
  • Okava targets a cost near $100 per month and uses delivery technology from Vivani Medical to support long-term adherence with a single implant.
  • Veterinarians cite prior off-label use of human GLP-1s in feline diabetes and highlight open questions on effectiveness, side effects, and owner acceptance as Okava eyes larger trials and an FDA filing as early as 2027–2028.