Overview
- Francisco González scored the winner in the 52nd minute from a Luis Pávez cross at Estadio Codelco El Teniente in Rancagua.
- Deportes Tolima went down to 10 men after Kelvin Flórez was sent off in the first half, and O'Higgins later lost Felipe Ogaz to a second yellow in the second half.
- The second leg is scheduled for Wednesday, March 11, with O'Higgins protecting a one-goal advantage in the tie.
- O'Higgins set up in a 4-3-3 under Lucas Bovaglio, while Lucas González’s Tolima used a 4-5-1 with Neto Volpi in goal.
- Uruguayan referee Andrés Matonte officiated the match, which was carried on ESPN and Disney+ according to pre-match listings.