Overview
- Both teams enter 12-0 as the lone remaining unbeaten programs in the FBS.
- The winner is widely projected to claim the No. 1 College Football Playoff seed, with the loser still expected to reach the field and remain in strong position for a first-round bye.
- Sportsbooks list Ohio State about a 4-point favorite after an opening number near -6.5, with the total around 47.5.
- Ohio State leads the nation in scoring and total defense, allowing roughly 206 yards per game, while Indiana brings a top-tier offense and an FBS-best +17 turnover margin and ranks second nationally in scoring defense.
- Heisman contenders Julian Sayin and Fernando Mendoza headline the quarterback matchup, with Sayin completing 78.9% for 3,065 yards and 30 TDs and Mendoza throwing 32 TDs.