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NIT Rourkela Reports Plant-Based ZnO Nanoparticles With Enhanced Lab Antibacterial Activity

A plant-derived phyto‑corona stabilizes nanoparticles, controlling zinc‑ion release for dual‑action antibacterial activity.

Overview

  • Peer‑reviewed findings published in Surfaces and Interphases detail an eco‑friendly synthesis using extracts of marigold, mango and eucalyptus to form zinc oxide nanocrystals.
  • The plant extracts reduce zinc salts and leave phytocompounds on the surface, creating a stabilizing phyto‑corona that supports sustained antibacterial action.
  • Marigold‑based nanoparticles were reported to be about twice as effective as chemically synthesized particles or extracts alone, including against E. coli and Bacillus subtilis in lab tests.
  • The team describes zinc ions disrupting bacterial membranes, generating reactive molecules and blocking vital processes, with phytochemicals adding inherent antibacterial effects.
  • The study, led by Prof. Suman Jha with scholars Kumari Subham, Sonali Jena and Monalisha Ojha, is positioned as a scalable, affordable platform pending further validation, safety assessment and development.