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New York City Confirms First Case of More Severe Mpox Clade I Linked to Travel

Health officials are urging at-risk New Yorkers to get the two-dose JYNNEOS vaccine.

Overview

  • The Health Department confirmed a clade I infection in a recent international traveler and issued a health advisory to providers.
  • Officials report no known local transmission or additional clade I cases in the five boroughs, saying the current risk is low.
  • Clade I is associated with more severe illness than clade II, which fueled about 4,000 New York City cases in 2022.
  • The city urges at-risk people to complete the two-dose JYNNEOS series with doses at least 28 days apart; those who previously had mpox do not need vaccination.
  • People who should consider vaccination include men who have sex with men, trans and nonbinary people, travelers to areas with mpox activity, and recent close contacts within 14 days; vaccine sites are listed at nyc.gov/mpox or by calling 311.