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New Studies Link Ultra-Processed Foods to Higher Dementia, Heart and Mortality Risks

A special issue of the American Journal of Public Health strengthens evidence that processed foods harm brain and cardiometabolic health and raises pressure for regulation as federal definition work remains unfinished.

Overview

  • The American Journal of Public Health published a 17-article special issue on June 3–4, 2026 that includes a Health and Retirement Study analysis showing the highest consumers of ultra-processed foods had a 58% higher risk of dementia and a 46% higher risk of cognitive impairment than the lowest consumers.
  • A Tufts analysis of NHANES data (1999–2018) found that higher shares of calories from ultra-processed foods were tied to worse weight, blood sugar, blood pressure and cholesterol and a slightly higher risk of death even after researchers adjusted for overall nutrient quality.
  • Authors say processing-specific factors — such as industrial additives, altered food structure and chemicals from packaging — may drive harms beyond nutrients and point to plausible biological paths like gut-microbiome changes and inflammation.
  • A nationally representative Cornell survey of 2,000 U.S. adults found broad bipartisan support for government action, with 77% backing large warning labels, 64% favoring limits on marketing to children and 87% wanting pre-market testing of synthetic additives.
  • Researchers and public-health advocates are urging regulatory steps, litigation and subsidy shifts while noting the evidence is observational, based on self-reported diet and survey cognitive tests, so findings prompt policy debate rather than definitive proof of causation.