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New Human Blood System ‘Gwada Negativo’ Confirmed With One Known Carrier

The addition brings the global count to 48 recognized systems.

Overview

  • A woman from Guadeloupe is the only known carrier of a newly identified human blood system.
  • The French Blood Establishment confirmed the finding and named the system “Gwada negativo” for the patient’s Guadeloupe origin.
  • International transfusion experts recognized the system at a scientific meeting in Milan, placing it on the official roster of blood group systems.
  • Specialists say she may be incompatible with any donor, making her effectively compatible only with herself for transfusion.
  • The case began about 15 years ago with an unknown antibody found in Paris, and DNA sequencing in 2019 traced it to a mutation inherited from both parents, prompting a global search for other carriers.