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New Ciliate Can Become a Cannibalistic 'Supergiant' Predator

Researchers find the shift is a regulated developmental program that lets a small fraction of cells exploit clonal relatives when bacterial prey is scarce.

Overview

  • Researchers working with samples from a seawater filtration system in Curaçao documented clonal populations of a previously undescribed ciliate, named Euplotes gigatrox, that sometimes produce much larger 'supergiant' cells.
  • In the supergiant state cells change shape and behavior, hunting by walking in circular paths and tumbling poorly in water, and they capture and swallow clonal relatives at about one prey every 10 minutes.
  • Single-cell transcriptome sequencing shows supergiants express a distinct gene program that alters cell cycle, protein production, and membrane organization, identifying the state as a regulated developmental stage rather than a random anomaly.
  • Cells that revert from the supergiant state retain a molecular signature that slows or suppresses re-formation, and supergiants remain rare in lab populations—under 5 percent—consistent with a bet-hedging ecological strategy triggered when small prey is limited.
  • The finding gives scientists a new, single-cell model for studying organism-like development and behavioral complexity, but researchers note most evidence comes from cultured clones from one site so the role of this strategy in nature remains to be tested.