Overview
- The Nature Metabolism review, published Friday, argues that fructose plays a unique role in disease beyond simply adding calories.
- The authors say fructose metabolism bypasses key checks and quickly drains cells of ATP energy, and the body can also make fructose from glucose.
- They report these pathways boost fat creation, raise liver fat, drive insulin resistance, and push up blood triglycerides.
- The team points to soda and other sugary drinks as high risk because they deliver large doses without fiber or nutrients.
- Much of the evidence comes from cell and animal work, so the authors call for larger human studies to confirm effects in people.