Overview
- Lionel Messi was limited to one shot on target that Brian Schwake saved, delaying his 900th career goal after entering with 899.
- Nashville finished with a 15–8 shot advantage while Inter Miami controlled 59% possession in the scoreless draw at Geodis Park.
- The Round of 16 will be decided in Fort Lauderdale, where the away‑goals rule applies before potential extra time and penalties if still level.
- The winner will face Club América or the Philadelphia Union in the quarterfinals after América took a 1-0 lead in their first leg.
- Inter Miami began this stage as a seeded entrant, whereas Nashville advanced from Round One after a 7-0 aggregate win over Atlético Ottawa.