Overview
- Kickoff is at 21:00 local time, with free-to-air coverage on Italia 1 and streaming on Mediaset Infinity.
- The winner will advance to face Inter in the semi-final.
- Napoli arrive from a 3-2 league win at Genoa sealed by a late Hojlund penalty and will be without the injured Scott McTominay.
- Como come in off a weekend without a match and reached this stage by eliminating Südtirol, Sassuolo and Fiorentina.
- The teams drew 0-0 at the Maradona on November 1, when Como missed a penalty saved by Vanja Milinkovic-Savic.