Overview
- The University of Melbourne meta-review, published Tuesday, analysed 85 trials of ten common IVF add‑ons and found only weak evidence that three interventions — EmbryoGlue, endometrial scratching and physiological ICSI — might help live‑birth rates.
- Seven widely offered extras, including preimplantation genetic testing for aneuploidy, endometrial receptivity testing, corticosteroids, platelet‑rich plasma, acupuncture and intralipids, showed little or no evidence of benefit.
- Researchers warn patients are vulnerable to marketing and social media claims and often pay between about $150 and $5,000 for add‑ons that may waste money and reduce their ability to afford further IVF cycles.
- The authors published a companion paper and launched an independent evidence website to give patients clear, up‑to‑date information and urged clinics to present balanced, evidence‑based advice.
- Professional groups such as the Fertility Society of Australia and New Zealand back moves toward national oversight, which could standardise regulation and patient resources after a 2025 review call prompted by earlier sector failures.