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Mackenzie Paul, TikTok Creator and Medical Student, Dies at 26 After Leukemia Relapse

Her husband announced the news in a Facebook video following a rapid relapse months after doctors reported remission.

Overview

  • The Michigan State University medical student disclosed an acute myeloid leukemia diagnosis in October 2023.
  • On the morning she died, she became unwell, was taken to an emergency room, moved to intensive care, and passed away shortly afterward, her husband said.
  • Brandon Paul described how the cancer returned quickly despite a period of remission in summer 2025.
  • He remembered her as the strongest and most disciplined person he knew and said he will need a lifetime to process the loss.
  • Paul chronicled her treatment with roughly 28,000–30,000 followers, and in her final clip she spoke of severe mouth pain that made eating difficult.