Particle.news
Download on the App Store

Lilly to Buy Adverum in Gene‑Therapy Deal Worth Up to $12.47 a Share

The offer targets Ixo-vec, a one-time treatment for wet age-related macular degeneration now in a late-stage trial.

Overview

  • Lilly will launch a tender offer of $3.56 in cash per Adverum share plus non-transferable CVRs worth up to $8.91, for a total potential $12.47 per share.
  • CVR milestones include U.S. approval of Ixo-vec within seven years and surpassing $1 billion in annual global sales within ten years of closing.
  • The companies expect the deal to close pending shareholder and regulatory approvals, with Reuters citing a fourth-quarter 2025 target and other outlets pointing to early 2026.
  • Ixo-vec is being evaluated as a one-time intravitreal gene therapy for wet AMD in the ARTEMIS Phase 3 program and has FDA Fast Track and RMAT, EMA PRIME, and a UK Innovation Passport.
  • Shares moved higher after the announcement, and Lilly framed the acquisition as part of its broader push into durable, one-time genetic medicines.