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Joe Manganiello Announces Memoir Detailing Secret Seven‑Year Autoimmune Ordeal

The actor says his new book explains how failed medical treatments, major surgeries and a spiritual search led him to reclaim health and examine family inheritance.

Overview

  • Manganiello and publisher Simon & Schuster announced Bloodlines this week with a preorder and an Oct. 13 release date.
  • The publisher’s synopsis says a seven‑year cascade of autoimmune‑related illnesses attacked his skin, thyroid, eyes, lungs and digestive system and produced multiple near‑death episodes.
  • Manganiello posted an Instagram video describing heavy medication, harsh side effects from high‑powered biologic drugs, ‘‘very serious’’ operations that he says mutilated parts of his body, and a life‑saving organ amputation.
  • When conventional medicine offered no clear answers, the memoir recounts a globe‑spanning turn to shamans, rituals and deep genealogical research that uncovered an ancestor who survived the Armenian genocide.
  • The book leaves some medical specifics undisclosed and is likely to prompt public conversation about limits of current autoimmune treatments and the appeal of alternative and ancestral approaches to chronic illness.