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Irish Study Finds Surge in Spinal Cord Damage Linked to Recreational Nitrous Oxide Use

The Beaumont Hospital case series reports lasting neurological harm in young people after inhaling legally available gas.

Overview

  • Research led by consultant neuroradiologist Seamus Looby, published in the American Journal of Neuroradiology, documents 14 cases at Beaumont Hospital from 2021 to 2024 after none from 2012 to 2020.
  • Patients had a median age of 20, and most improved with treatment, though none achieved full recovery.
  • The team attributes the injury to disruption of vitamin B12 metabolism causing subacute combined degeneration of the spinal cord, with numbness and balance problems among early symptoms.
  • Youth workers report increasing recreational use via balloons, and Looby urges greater public awareness and education about permanent risks.
  • Nitrous oxide remains legally sold for catering and industrial uses in Ireland, while the UK outlawed possession for getting high in November 2023.