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International Panel Backs Fast MRI, Risk-Based Pathways for Prostate Cancer Screening

New guidance arrives before a UK ruling on whether to expand screening.

Overview

  • Twenty-one urologists, radiologists and pathologists from Europe and the US issued an expert consensus, compiled by Imperial College London and presented at the European Association of Urology congress in London.
  • The panel recommends sub‑15‑minute MRI scans for men aged 50 to 70, starting from 45 for Black men, with PSA testing used first to triage candidates and repeat screening tailored to individual risk.
  • The approach aims to find clinically significant cancers while reducing overdiagnosis, unnecessary biopsies and pressure on MRI services.
  • The recommendations will inform Prostate Cancer UK’s Transform trial, which is evaluating combinations of PSA tests, genetic panels and 10‑minute MRI scans for potential population screening.
  • Supporting research from the PRAISE‑U study suggests a risk‑based pathway after PSA—using tools such as digital rectal examination or ultrasound—could cut MRI referrals by up to 60%, as the UK National Screening Committee weighs final guidance after a draft opposing routine PSA screening except for BRCA1/2 carriers.