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Gilead Lifts 2026 Sales Outlook, Warns of Loss on $11.5 Billion Deal Charge

The guidance flip highlights the near-term cost of an acquisition spree.

Overview

  • Gilead beat first-quarter estimates with $6.96 billion in revenue and adjusted earnings of $2.03 per share.
  • The company raised 2026 revenue guidance to $30.0–$30.4 billion and lifted the 2026 target for its HIV prevention shot Yeztugo to $1 billion.
  • Management now projects an adjusted 2026 loss of $1.05 to $0.65 per share because of an $11.5 billion in-process R&D charge that will be recorded in the second quarter.
  • IPR&D is an accounting write-off for acquired, not-yet-approved R&D assets, and executives said earnings would be unchanged without the charge.
  • Product trends were mixed as Biktarvy rose to about $3.36 billion, Yeztugo posted $166 million and topped forecasts, cell therapy revenue fell 12% to $407 million, and cancer drug Trodelvy climbed 37% to $402 million; shares dipped about 1%–2% after the update.