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Genomes Show Cave Lion Was a Distinct Species Split More Than a Million Years Ago

A time-series of 12 cave-lion genomes links brief, climate-driven interbreeding with modern lions to glacial pulses and finds a rapid end‑Pleistocene collapse despite large late populations.

Overview

  • A study published Tuesday in the journal Cell sequenced 12 complete cave-lion genomes and compared them with about 20 modern lion genomes to build a dated record of the species’ history.
  • Genomic analyses indicate cave lions (Panthera spelaea) separated from modern lions more than one million years ago, forming a long‑running, evolutionarily distinct lineage.
  • Researchers found repeated, short episodes of interbreeding tied to cold glacial intervals, with modern‑lion ancestry in cave lions rising during those colder phases.
  • The team identified cave‑lion‑specific mutations concentrated in genes for brain function, vision, growth, and circulation, suggesting candidate adaptations to Pleistocene cold and seasonal environments.
  • Demographic reconstructions show cave-lion populations were sizeable shortly before a rapid, range‑wide extinction about 13,000–14,000 years ago, implying prey loss and ecological change rather than long‑term genetic decline caused the die‑off.