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Fayette County Coroner Confirms Tianeptine Overdose Death, Calls for Nationwide Ban

The case spotlights a legal gap with the opioid-like drug still sold in Pennsylvania.

Overview

  • The coroner said toxicology showed overdose-level tianeptine and he ruled the death was caused by that drug.
  • Tianeptine has no FDA approval and is sold in gas stations, vape shops, and online under names like Neptune's Fix, Zaza, TD Plus, and Pegasus.
  • The FDA has documented cases of slow or stopped breathing, coma, and death from tianeptine, with higher risk for people with a history of opioid use disorder.
  • The substance remains legal to sell in Pennsylvania even as at least a dozen states have banned it, and the coroner is urging a nationwide ban or Schedule I listing.
  • Dr. Bob Baker urged use of Narcan in suspected cases because tianeptine acts on opioid receptors and can depress breathing.