Particle.news
Download on the App Store

Eli Lilly’s Q4 Beat and Bullish Outlook Give Way to Stock Drop on Low-Cost GLP-1 Pills

Sales were led by injectable GLP-1 treatments that now face pressure from cheaper pills.

Overview

  • The company posted Q4 2025 adjusted EPS of $7.54 on revenue of $19.29 billion, topping analyst estimates on both measures.
  • Mounjaro generated about $7.41 billion and Zepbound $4.26 billion in the quarter, with triple-digit year-over-year growth driven by volume.
  • Lilly guided 2026 revenue to $80–$83 billion and adjusted EPS to $33.50–$35, both ahead of Wall Street forecasts.
  • Shares jumped after the earnings release, then fell about 6% Thursday following Hims & Hers’ launch of a compounded semaglutide pill priced at $49 for the first month and $99 for months two through five.
  • Competitive pricing comparisons highlight pressure on injectables, as Lilly lists a $299 cash price for its lowest-dose Zepbound while Novo Nordisk offers a $149 Wegovy pill, and Lilly is advancing an oral candidate, orforglipron, with regulatory filings in the U.S., EU, and Japan.