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Ebola Outbreak in Eastern DRC Tops 1,100 Cases and Spreads to Uganda and France

WHO modelling shows a high short-term risk of importation to South Sudan with no licensed vaccine available for the Bundibugyo strain.

Overview

  • The outbreak, declared on 15 May, has grown to more than 1,100 confirmed infections and over 300 deaths in eastern DRC according to national health authorities.
  • Infections have crossed borders with roughly 20 confirmed cases reported in Uganda and a returning humanitarian doctor confirmed as the first imported case in France.
  • A WHO modelling study gives South Sudan about a 69% chance of receiving at least one case within 12 weeks and projects a central scenario of thousands more confirmed cases by September if transmission continues.
  • There is no licensed vaccine or strain-specific approved treatment for Bundibugyo ebolavirus, prompting international action that includes CDC Level 1 activation, CEPI funding for vaccine development, shipments of experimental therapeutics and planned clinical trials.
  • Control efforts are hampered by a roughly six-week detection delay from lab assay mismatches, under-resourced contact tracing, health-worker infections, and insecurity and displacement that make access and isolation of cases difficult.