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Dupixent Surge Lets Sanofi Reset Strategy as Regeneron Posts Strong Quarter

Robust Dupixent demand is giving Sanofi's new CEO room to cut and refocus R&D while simplifying the economics of the partner deal for Regeneron.

The logo of French drugmaker Sanofi at the 10th edition of the VivaTech technology startups and innovation fair in Paris, France, June 18, 2026. REUTERS/Gonzalo Fuentes
The Regeneron Pharmaceuticals company logo is seen on a building at the company's Westchester campus in Tarrytown, New York, U.S. September 17, 2020. Picture taken September 17, 2020. REUTERS/Brendan McDermid

Overview

  • Sanofi raised its full-year sales forecast after Dupixent sales jumped about 38% to €5.15 billion and the company said operating income should grow slightly faster than sales.
  • Sanofi's newly installed CEO Belen Garijo has overhauled the leadership team, named a new head of R&D, and stopped development of several late-stage programs including amlitelimab, itepekimab, and balinatunfib as part of a strategic review.
  • Regeneron beat analyst estimates for the quarter with revenue of $4.29 billion and non-GAAP earnings of $14.29 per share, driven by Dupixent strength and a 52% rise in U.S. sales of high-dose Eylea.
  • Regeneron said it fully repaid the Sanofi Development Balance, which removes an outstanding collaboration payment, tightens margins and simplifies future financial flows between the partners.
  • Analysts and both companies say Dupixent will remain the main growth engine with projections toward roughly €24–25 billion in annual sales by 2030, a reality that is letting Sanofi focus acquisitions and R&D on immunology, rare diseases, and vaccines while changing how it judges late-stage projects.