Overview
- Fatty liver is very common and often shows no symptoms, yet it now ranks among leading causes of liver cancer in people who do not drink heavily.
- Clinicians say losing roughly 7–10% of body weight yields the biggest benefit for reversing fat buildup and improving early fibrosis, while even 3% can improve liver markers.
- Experts recommend at least 150 minutes of aerobic activity per week and two weekly strength sessions to protect muscle and boost metabolic health during weight loss.
- Noninvasive elastography is a practical test to detect fibrosis and track improvement, and primary-care teams should follow CDC guidance on one-time hepatitis B and C testing and hepatitis B vaccination.
- Unregulated ‘detox’ supplements are discouraged and newer drugs such as GLP-1 agonists may help in advanced MASLD only when used with supervised lifestyle measures to avoid muscle loss.