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Cross-Continental Study Finds U.S. Reports Far Higher Long COVID Brain Fog Than India, Nigeria and Colombia

Researchers say cultural norms, stigma and unequal access to mental and neurological care best explain the gap, not differences in the virus.

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Overview

  • Published Jan. 28 in Frontiers in Human Neuroscience, the analysis compared more than 3,100 adults treated at academic centers in Chicago, Medellín, Lagos and Jaipur.
  • Among non-hospitalized patients, 86% in the U.S. reported brain fog versus 63% in Nigeria, 62% in Colombia and 15% in India.
  • Nearly 75% of similar U.S. patients reported depression or anxiety, compared with about 40% in Colombia and fewer than 20% in Nigeria and India.
  • Sleep problems also diverged, with nearly 60% of U.S. patients reporting insomnia versus roughly one-third or fewer elsewhere.
  • Symptom patterns clustered by country income level, and the team is now testing Chicago-developed cognitive rehabilitation in cohorts in Colombia and Nigeria while calling for culturally adapted screening and long-term follow-up.