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Childhood Trauma Linked to Higher Endometriosis Risk

Researchers say childhood trauma reshapes immune function through altered stress responses to influence endometriosis risk.

Overview

  • The nationwide cohort study of over 1.3 million Swedish women born between 1974 and 2001 identified more than 24,000 endometriosis cases using national healthcare registers.
  • Women exposed to any adverse childhood experience such as parental substance abuse, mental illness or financial instability faced a 20% higher risk of receiving an endometriosis diagnosis.
  • Individuals with five or more traumatic factors saw a 60% increased risk, while childhood exposure to violence more than doubled the likelihood of developing the condition.
  • Endometriosis affects about one in ten women in the United States and occurs when uterine-like tissue grows outside the uterus, leading to chronic pain, inflammation and fertility issues.
  • The findings highlight the importance of a holistic approach in women’s healthcare that integrates psychological history into endometriosis diagnosis and treatment.