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CEPI Backs Next-Gen Zaire Ebola Vaccine With $30 Million Routed Through MSD

The collaboration targets higher yields with greater thermostability to support affordable, reliable supply in outbreak-prone regions.

Overview

  • CEPI finalized an agreement to provide up to $30 million to MSD, which will distribute funding to SK bioscience and Hilleman Laboratories.
  • Hilleman Laboratories will lead clinical development of an updated vaccine based on MSD’s WHO-prequalified Zaire ebolavirus shot.
  • SK bioscience and Germany-based IDT Biologika will develop the drug substance and drug product manufacturing processes, including work at SK’s Andong plant.
  • The program centers on manufacturing process improvements and scale-up to boost yield and enhance thermostability for use in low-resource settings.
  • CEPI CEO Richard Hatchett said the support aims to ensure a sustainable, more affordable supply as Zaire Ebola continues to resurge in parts of Africa such as the Democratic Republic of the Congo.