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Bryan Johnson Diagnosed With Autoimmune Gastritis and Launches Experimental Immune Work

He received a 1,000 mg IV iron infusion that restored ferritin and has begun large-scale immune sequencing to guide unproven therapy attempts.

Overview

  • Johnson’s diagnosis was confirmed by an upper endoscopy with multiple stomach biopsies after years of unexplained low ferritin that clinicians had previously missed.
  • He received a single 1,000 mg monoferric intravenous iron infusion and reported a rapid ferritin rise to about 205 ng/mL two weeks after treatment.
  • Johnson’s team is performing repeat biopsies, deep cytokine and T‑cell profiling, and sequencing of large numbers of immune cells as the basis for data‑driven interventions.
  • He has announced plans to explore engineered immune approaches such as CAR‑T or AI‑designed biologics, measures that experts describe as novel but early and unproven.
  • Clinicians note autoimmune gastritis often causes silent iron and B12 malabsorption and raises long‑term stomach cancer risk, and Johnson’s case underscores the limits of intensive longevity regimens while raising public awareness and research interest.