Overview
- Kyle Shanahan confirmed Friday that Purdy will start after practicing all week with no injury designation.
- Purdy missed two games with a turf-toe variant and a left shoulder issue, while Mac Jones went 2-0 in relief and is questionable with a knee injury.
- The final Week 4 report lists WR Jordan Watkins and DT C.J. West out, with Jauan Jennings, Ricky Pearsall, Renardo Green and Connor Colby questionable.
- Nick Bosa underwent surgery Friday for a torn right ACL and will miss the remainder of the season, with the procedure described as clean.
- Tight end George Kittle remains on injured reserve, and GM John Lynch said Brandon Aiyuk is not close to returning from his 2024 knee injuries.