Overview
- The peer-reviewed study, published Thursday in Cell Reports Physical Science, found 30-minute daily sessions for three weeks worked as well as fluoxetine in a stress-induced mouse model.
- The lenses send two weak electrical signals that only become active where they overlap at the retina, which lets the pulse reach targeted mood-related brain circuits.
- Recordings showed lost connectivity between the hippocampus and prefrontal cortex came back, alongside a 48% drop in blood corticosterone and a 47% rise in serotonin.
- An integrative machine-learning readout grouped treated mice with healthy controls rather than with untreated depressed mice.
- The device remains a wired prototype at an early stage, with plans for a wireless version, longer-term safety testing in larger animals, personalized dosing, and then clinical trials.